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Clin Shoulder Elbow > Volume 14(2); 2011 > Article
Clinics in Shoulder and Elbow 2011;14(2):172-178.
DOI: https://doi.org/10.5397/CiSE.2011.14.2.172    Published online December 31, 2011.
Inflammatory Cytokine Expressions of the Subacromial Bursitis and Glenohumeral Joint Synovitis in the Patients with Full Thickness Rotator Cuff Tear
Sung Kyu Kim, Hyung Nam Kim, Eun Sun Moon, Keun Young Lim, Nam Young Cho, Myung Sun Kim
Department of Orthopaedic Surgery, Chonnam National University College of Medicine, Gwangju, Korea. mskim@jnu.ac.kr
회전근 개 전층 파열 환자에서 견봉하 점액낭염과 관절와 상완 관절 활액막염의 염증성 사이토카인의 발현 양상
김성규·김형남·문은선·임근영·조남영·김명선
전남대학교 의과대학 정형외과학교실
Abstract
PURPOSE
The purpose of this study was to compare expression patterns of inflammatory cytokines between subacromial bursitis and glenohumeral (GH) joint synovitis in full thickness rotator cuff (RC) tear patients with severe pain. MATERIALS AND METHODS: We were able to obtain enough tissue from nine subacromial bursitis and GH synovitis patients at the same time during surgery and evaluate them. We compared mRNA expression of inflammatory cytokines between the two groups using Reverse Transcription-Polymerase Chain Reaction (RT-PCR).
RESULTS
Relative mean mRNA expression of IL-1beta, IL-6, TNF-alpha, COX-1, COX-2 and SDF-1 in the tissues of subacromial bursitis and GH synovitis patients did not show significant differences.
CONCLUSION
GH synovitis may be another source of shoulder pain with subacromial bursitis in full thickness RC tear patients with severe pain.
Key Words: Rotator cuff tear; Subacromial bursitis; Glenohumeral synovitis; Inflammatory cytokine; RT-PCR


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