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Korean Journal of Clinical Oncology > Volume 6(1); 2010 > Article
ORIGINAL ARTICLE
Korean J Clin Oncol. 2010;6(1): 33-39.         doi: https://doi.org/10.14216/kjco.10005
The Influence of Proximal Resection Margin in Adenocarcinoma of the Gastroesophageal Junction on survival
Cheon Soo Park, Tae Hwan Kim, Beom Su Kim, Kab Choong Kim, Sung Tae Oh, Byung Sik Kim, Jeong Hwan Yook
Department of Surgery, Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea
위식도접합부 선암에서 근위부 절제연의 길이가 예후에 미치는 영향
박천수, 김태환, 김범수, 김갑중, 오성태, 김병식, 육정환
울산대학교 의과대학 서울아산병원 외과학교실
Corresponding Author: Jeong Hwan Yook ,Tel: +82-2-3010-3496, Fax: +82-2-3010-6701, Email: jhyook@amc.seoul.kr
Received: May 20, 2010;  Accepted: June 23, 2010.
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ABSTRACT
Purpose: To determine the length of proximal resection margin for patients with adenocarcinoma of the gastroesophageal junction(GEJ). Materials and
Methods: We reviewed retrospectively the medical records of the 289 patients who underwent surgery for adenocarcinoma of GEJ in our institution between Janury 2001 and December 2003. Result: The 289 patients who underwent surgery for adenocarcinoma of GEJ were divided on T stage, below T1 group(T1,n=66) and above T2 group(T2-4, n=223). We studied the influence of proximal resection margin in adenocarcinoma of the GEJ on survival. In T1(n=66) group, univariate analysis revealed no influence of proximal resection margin in adenocarcinoma of GEJ on survival. In T2-4(n=223) group, univariate analysis revealed influence of proximal resection margin on survival ; 0.5cm, 2.0cm, 3.0cm, 3.5cm, 4.0cm. Multivariate analysis show that only influence of proximal resection margin on survival; 0.5cm (p=0.009, HR:2.232, 95% CI:1.218-4.091)
Conclusion: We should be undergoing surgery for T2-4 gastric adenocarcinoma of GEJ with safely proximal resection margin; >0.5cm for survival improvement.
Keywords: Adenocarcinoma of the Gastroesophageal Junction | Length of Proximal Resection Margin
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