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Korean Journal of Clinical Oncology > Volume 16(2); 2020 > Article
Korean J Clin Oncol. 2020;16(2): 138-141.         doi: https://doi.org/10.14216/kjco.20021
Perianal extragastrointestinal stromal tumor
Ayoung Kang1 , Sung Hwan Cho1 , Byung-Soo Park1 , Gyung Mo Son1 , Hyun Sung Kim1 , Jae-Joon Kim2 , Su Jin Kim2 , Dong Hoon Shin3 , Tae Un Kim4
1Department of General Surgery, Pusan National University Yangsan Hospital, Yangsan, Korea
2Department of Internal Medicine, Pusan National University Yangsan Hospital, Yangsan, Korea
3Department of Pathology, Pusan National University Yangsan Hospital, Yangsan, Korea
4Department of Radiology, Pusan National University Yangsan Hospital, Yangsan, Korea
Corresponding Author: Byung-Soo Park ,Tel: +82-55-360-2124, Fax: +82-55-360-2154, Email: colonsurgeon@naver.com
Received: September 22, 2020;  Accepted: December 8, 2020.
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An extragastrointestinal stromal tumor (EGIST) is a gastrointestinal stromal tumor that arises outside of the gastrointestinal tract. Most EGISTs are located in the omentum, mesentery, and retroperitoneum. The occurrence of an EGIST at the perianal region is very rare. Herein, we report our experience with EGISTs in the perianal area and review the literature. A 70-year-old man presented to our hospital with a 2-year history of anal discomfort. A pelvic magnetic resonance imaging scan showed a homogenous, well-defined, soft tissue density mass. The patient underwent mass excision, and the pathological examination confirmed that the mass was an EGIST. The size of the tumor was 4.3×3.2 cm, and the mitotic count was 1 per 50 high-power fields. The tumor cells were immunohistochemically positive for KIT and CD34 but were negative for S-100 and alpha-smooth muscle actin. There were no other abnormal findings in the gastrointestinal tract; upon pathological review, this case was confirmed as perianal EGIST. Therefore, EGIST should be considered as a differential diagnosis of perianal masses.
Keywords: Extragastrointestinal stromal tumor | Gastrointestinal stromal tumor | Perianal neoplasm
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